Sex-Linked Inheritance - Colour Blindness Inheritance

Sex-linked inheritance is caused by a gene defect on the X chromosome. For example, colour blindness.

Females have two X chromosomes, therefore they need to have two copies of alleles to express the trait.

Males have one X chromosome, therefore they need only one copy of allele to express the trait.

A cross between a father who is normal and a mother who is a carrier of colour blindness

=> Normal is dominant whereas colour blind is recessive
=> R - normal, r - colour blind
=> For male: XRY (normal), XrY (colour blind)
=> For female: XRXR (normal), XRXr (carrier), XrXr (colour blind)

Parent phenotypes:        Father, normal  X  Mother, carrier
Parent genotypes:                    XRY           X          XRXr
Gametes:                              XR           Y            XR          Xr
F1 genotypes:                  XRXR      XRXr       XRY       XrY
F1 phenotypes:        Daughter,  Daughter,     Son,        Son,
                                    normal       carrier          normal    colour blind
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